I don't think I've ever seen a remotely decent anime/manga with a female main character. It's not even because they're romance-y, because a lot of my favorite series have romance. Either these types of series are romance with very poor writing (or just too much from a girl's point of view for a guy to enjoy), or it's too Japanese (Lucky Star), or it's a shitty comedy (Azumanga Daioh), or a combination of those.